IHMRI affiliation

Theme:Mental health and the ageing brain
Role:Affiliated Stakeholder Advisory Panel (ASAP)
Level:IHMRI Senior Fellow

Research focus

Molecular chaperone proteins are the body’s front-line defenders against the clumping of proteins into the large deposits that are associated with many human diseases, including Alzheimer’s disease, Parkinson’s disease and Motor Neurone Disease (MND). By identifying innovative approaches to activate these molecular chaperones, my work aims to develop new drugs to treat, and ultimately prevent these diseases.

Publications and funding


  • Member of the Australian Biochemistry and Molecular Biology Society

IHMRI research team

PhD candidates

Caitlin Johnson Investigating chaperone function at the single molecule level
Kristian Claesson Validating heat shock factor 1 as a potential therapeutic target for the treatment of neurodegener
Nicholas Marzano Developing a protein folding sensor that can be used for single molecule assays
Shannon McMahon Investigating the role of proteostasis pathways in regulating the intracellular protein aggregation of firefly luciferase: a model system to study protein aggregation in cells
Lauren Rice Single-molecule studies of chaperone proteins and their interactions with client proteins