IHMRI affiliation

Theme:Diagnostics and therapeutics

Research focus

  • Microbiology
  • Molecular biology
  • Diagnostic microbiology research and development
  • Sexually transmitted infections
  • Antibiotic resistance
Research projects

2018-2021

Other investigators: Clinical Professor Spiros Miyakis, Dr J Payne

  • In Vitro activity of vancomycin, daptomycin and ceftarolline in combination with beta-lactams and common antistaphylococcal agents against daptomycin-susceptible and daptomycin non-susceptible MRSA with reduced susceptibility to Vancomycin
  • Penicillin and ceftriaxone combined therapy for Viridians group Streptococcus endocarditis

Publications and funding

  • Goire, N., Trembizki, E., Buckely, C., Hogan, T., Lewis, D. A., . . .Whiley, D. M., & Lahra, M. M.(2016). Mixed gonococcal infections in a high-risk population, Sydney, Australia 2015:implications for antimicrobial resistance surveillance? J Antimicrob Chemother, 72(2), 409-407.doi: 10.1093/jac/dkw406
  • Enriquez, R. P., Goire, N., Kundu, R., Gatus, B. J., & Lahra, M. M. (2016). A comparison of agar dilution with the Calibrated Dichotomous Sensitivity (CDS) and Affiliation Agreement 4 Etest methods for determining the minimum inhibitory concentration of ceftriaxone against Neisseria gonorrhoeae. Diagn Microbial Infect Dis. doi: 10.1016/j.diagmicrobio.2016.04.016.
  • Goire, N., Harnett, G. B., O’Reilly, L. C., Ingram, P.R., Leung, M. J., Speers, D. J., … Inglis, T. J.(2016). The implications of endemic IMP-4 carbapenemase for clinical laboratory susceptibilitytesting. J Microbial Methods, 124, 10-12. doi: 10.1016/j.mimet.2016.03.001
  • Buckley, C., Trembizki, E., Baird, R. W., Chen, M., Donovan, B., Freeman, K., Goire, N., .. .Whiley, D .. M. (2015). Multitarget PCR Assay for Direct Detection of Penicillinase-Producing Neisseria gonorrhoeae for Enhanced Surveillance of Gonococcal Antimicrobial Resistance. J Clin Microbial, 53(8), 2706-2708. doi: 10.1128/jcm.00540-154
  • O’Reilly, L. C., Goire, N., Fisk, R. E., & Speers, D. J. (2015). Molecular epidemiology of Neisseria gonorrhoeae using multi-antigen sequence typing and pulse-field gel electrophoresis in highly endemic Western Australian populations. BMC Infect Dis, 15, 272. doi: 10.1186/s12879-015-0988-7
  • Blyth, C. C., Pereira, L., & Goire, N. (2014). New Delhi metallo-beta-lactamaseproducing enterobacteriaceae in an Australian child who had not travelled overseas. Med J Aust, 200(7),386.
  • Goire, N., Lahra, M. M., Chen, M., Donovan, B., Fairley, C. K., Guy, R., … Whiley, D. M. (2014).Molecular approaches to enhance surveillance of gonococcal antimicrobial resistance. Nat Rev Microbial, 12(3), 223-229. doi: 10.1038/nrmicro3217 
  • Speers, D. J., Fisk, R. E., Goire, N., & Mak, D. B. (2014). Non-culture Neisseria gonorrhoeae molecular penicillinase production surveillance demonstrates the longterm success of empirical dual therapy and informs gonorrhoea management guidelines in a highly endemic setting. J Antimicrob Chemather, 69(5), 1243-1247. doi: 10.1093/jac/dkt501
  • Goire, N., Lahra, M. M., Ohnishi, M., Hogan, T., Liminios, A. E., Nissen, M. D., .. . Whiley, D. M. (2013). Polymerase chain reaction-based screening for the ceftriaxone-resistant Neisseria gonorrhoeae F89 strain. Euro Surveill, 18(14), 20444