IHMRI affiliation

Theme:Mental health and the ageing brain
Role:Affiliated Stakeholder Advisory Panel (ASAP)
Level:IHMRI Senior Fellow

Research focus

Distinguished Professor Huang (MBBS, PhD, DSc) is an NHMRC Research Leadership Fellow-L2 (2020-2015). He has made significant contributions to combat obesity induced by diet and antipsychotic drugs. His research: 1) discovered the central leptin resistance in the late stages of obesity, resulting in more than 1,000 research papers after his discovery; 2) discovered the satiety enhancer, oat β-glucan, for combating obesity, then incorporated into the NHMRC Australian Dietary Guidelines 2011, Food Standards ANZ 2015 & used by Uncle Toby’s for enhancing product development; 3) discovered the chemical site on antipsychotic drug responsible for obesity, leading to new drug development; 4) provided evidence that mental illness patients with diabetes have a worse cognitive function requiring combinational therapy. He published 253 research papers, had more than 13,223 citations (GS), supervised 26 PhD student completion, received the 2010 Vice Chancellor’s Award for Excellence in Research Supervision, and the 2014 Vice Chancellor’s Research Excellence Award for Senior Researcher of the Year.

Research projects

Publications and funding


  • Australian Neuroscience Society
  • Australian Biological Psychiatry Society
  • Endocrine Society
  • Australian Society for the Study of Obesity
  • North American Association for the Study of Obesity
  • Member of the Scientific Advisory Committee and Convener of the Developmental Neurobiology Panel of the Schizophrenia Research Institute
  • External Advisory Board of AstraZeneca Sweden

IHMRI research team

Research fellows

Dr Yinghua Yu T: +61 2 4298 1955 | E: yinghua@uow.edu.au

Research assistants

Hongqin Wang T: +61 2 4298 1568 | E: hongqin@uow.edu.au

PhD candidates

Peng Zheng The Role of DISC1 on regulating neurite outgrowth through mediating signalling pathway induced by D2/D1 receptor activation in the Prefrontal cortical Neurons
Yuanyi Xie Reversal of obesity and metabolic disorders associated with chronic antipsychotic treatment
Zehra Boz The role of olanzapine-induced autophagy in the hypothalamic energy regulatory pathwsay
Angila Dongal Prevention of brain inflammation affecting neural connectivity in schizophrenia
Jean (ZhiZhen) Wang The Molecular Mechanism of Microbiota-Gut-Brain Axis Influenced by Dietary Fibre Types
Serena (Xi) Chen Prevention and treatment of antipsychotic drug-induced cortical thinning.

Visiting researchers

Xue Li