Summary

In Australia, over 6,400 new cases of lymphoma and 4,200 cases of leukaemia are expected to be diagnosed in 2019.

This project investigate measures to prevent graft-versus-host disease (GVHD), a major complication in the treatment of blood cancers.

The project aims to uncover new and exciting treatment approaches for blood cancers that prevent GVHD, while retaining immune responses to cancer and infection.

Blood cancers are usually treated with high dose chemotherapy or radiation which knocks out the immune system.

About half of cancer patients will also undergo a donor stem cell transplant. While transplantation is a curative therapy for some people with blood cancer, there is a risk of developing GVHD.

GVHD is a debilitating and painful disease that attacks the organs, including the liver, skin and gut.

It occurs in around half of people who receive a donor stem cell transplant and can cause organ damage and failure, and in some cases can cause death.

Funding body

Cancer Council NSW

Scheme name

Project Grant

Years funded

2019 – 2021

Lead institution

University of Wollongong


Project leaders

Research area

Cancer