This project will examine whether overexpression of the FKBP5 gene may create a distinct pattern of gene expression in the brain and body that could be used to identify psychiatric patients who would benefit from drugs that suppress the gene’s activity.

FKBP5 is a key regulator of the stress response. Previous research by Dr. Matosin’s lab indicates that overexpression of the gene is linked to long term changes in cellular and systemic stress levels that may increase the risk of psychiatric illnesses such as depression, bipolar disorder and schizophrenia. (genetics; depression, bipolar disorder, schizophrenia).

Funding body

Brain & Behaviour Research Foundation

Scheme name

NARSAD Young Investigator

Years funded

2018 – 2020

Lead institution

University of Wollongong

Project leaders